FATS, OBESOGENS REDUCE LONGEVITY

That's Fats and Endocrine Disruptors etc.

CONTENTS

1. PRELUDE
2. HEALTH PYRAMID
3. FEW GOOD FATS
4. FIBER V. OBESOGENS

1. PRELUDE

I just came across Dr. Peter Rogers' video channel a few days ago at https://www.youtube.com/@PeterRogersMD/playlists. He's a low-fat vegan. I was a mostly raw food vegan from 1976-1996, living mainly on raw bananas blended with a little water, raw celery, cooked potatoes and raw sunflower seeds etc, but I started to develop a lot of health problems in 1996, so I've modified my diet ever since to try to overcome them. Muscle cramps, headaches, underweight and chronic fatigue were some of my main problems. Magnesium malate and citrate have mostly solved the muscle cramps and headaches IMO. Initially I added spirulina, chlorella, salt, eggs and yogurt to my diet. Fatigue and headaches may also have been symptoms of B12 deficiency, so the eggs and yogurt may have helped overcome them. I also added more nuts and seeds, and later, salmon, sardines and sometimes poultry. Last year my chiropractor used Applied Kinesiology on me and said I'm allergic to nuts, seeds, peanuts, oats and rice, but not wheat or rye. I hope to find a way to overcome such allergies. Anyway, in the last 20 years I've learned a lot more about health, especially lately. It occurred to me that I look and act younger than most others my age possibly because of my long-term largely raw food diet. I knew enough to avoid raw goitrogens, like the cabbage family etc. Upon discovering Dr. Rogers, I'm rethinking veganism. In part 2 below in his health pyramid, the top of it is vitamin B12, which is practically non-existent in vegan diet. Eggs don't have much B12. Milk has quite a bit, even skim milk. Sardines have plenty. Since he says fats are mostly dangerous, I figure I could try skim milk for B12. I learned that casein in dairy tends to cause cancer, but casein is broken down into dipeptides or tripeptides in digestion, so I guess casein would mainly only be a problem for those with low stomach acid or leaky gut. So I'm thinking of trying Walmart's Great Valu skim milk, since Great Valu is supposed to have no bovine growth hormones. And I may occasionally make kefir from it to maintain gut flora. He says starches are the best food for humans, and lentils may be best, though non-organic may have glyphosate. Sauerkraut is said to remove glyphosate. I heard that dairy farmers had to add sauerkraut to their dairy cow feed, because otherwise the glyphosate reduces milk production and the sauerkraut doesn’t have to be raw. I don’t know if all that is true. Dr. Rogers advises against using salt, but I heard that miso doesn’t have the normal negative effects of salt, so I’m thinking of using miso to provide a salty taste.

2. HEALTH PYRAMID

Peter Rogers MD
Beginner Nutrition

Health Pyramid:
1: B12;
2: 5-10% Veggies: Greens, Cauliflower;
3: 5-45% Fruits: Berries, Bananas, Oranges, Watermelon, Papaya;
4: 50-90% Starches: Potatoes, Sweet Potatoes, Rice, Beans, Oatmeal, Quinoa, Carrots;
5: Relationships; Exercise; Sunshine; Sleep; Religion; Spartan Vegan Toothpaste; Filtered Water
The most common deficiencies are fiber, magnesium, potassium and nitrates.
Don't worry about protein, fat, or calcium deficiency.
Avoid meat, sweets, oils, alcohol, caffeine, nuts, seeds, soy (too high in fats and estrogen), sodium, processed food.

3. FEW GOOD FATS

There are no good fats, except fiber fat "secret fat"

MOST FATS ARE BAD
OK, this is just a quick video to talk about fat because, it seems like some people can't get out of their mind this idea they need good fats. I've never in my whole life seen a person have any type of problem from a fat deficiency. I've never once seen a case, never seen a case in conference, never seen a case in a book. All day long I see tons and tons of diabetes, hypertension, obesity, that is so common they're all just considered normal aging. They're not. So I just want to say a few things about fat. I only have time to make one really detailed video when I got time to make videos at all. So I'm not gonna have a whole bunch of references and stuff. Just real quick on what's the scoop on fat. OK, Nathan Pritikin said it best. Fat is bad. I say the only good fats are fiber fat, meaning the fats that come from conversion of dietary fiber from plant foods in your gut into short chain fatty acids, and that's like acetate, propionate and butyrate.

LEAKY GUT
The colon lining cells, colonocytes, make the tight junctions that prevent leaky gut. Acetate and propionate are absorbed through the portal vein and go up to the liver. The liver can make them into whatever fats it wants to. And of course there's a little bit of other fats, the essential fats, like the omega-3 and the Omega 6, but you really only need those in pretty minimal quantities and you get plenty of them from just eating plant foods. By the way, if you want to read more about the details, McDougall wrote a pretty good summary of how you don't need anything but a little plant foods to get all the Omega-3s you need, and fish get them from the plants as well. So anyways, if you look at a carbohydrate, a molecule of glucose or fructose is a 6-carbon molecule. The body absorbs that and can metabolize it alright. If you look at a protein, a protein is broken down into little amino acids, typically absorbed as amino acid dipeptide, tripeptide, that's about it. So those are safe little things, but fats are not like that.

BLOOD SLUDGE
Fatty acids are absorbed as big things, relatively speaking. One of the most common saturated fats, palmitate has 16 carbons with no double bonds. And they can disrupt blood flow literally. We're not designed to eat any large amounts of fat on a routine basis. They make your blood thick with the formation of blood sludge. And the brain can't burn them. Astrocytes can burn some fats, but the neurons themselves run too fast with too many things going on. They need to burn glucose. And now the news gets much worse. Just like we know that fats are amphiphilic (like an amphibian lives on land and water), they're polar or nonpolar {one end is hydrophilic and the other end is hydrophilic} and can disrupt the gut-blood barrier and cause leaky gut. That's the main mechanism for autoimmune diseases that also allows gram negative endotoxins to get across the gut lining and cause meat-related endotoxemia. The thick blood predisposes to clot formation and decreases oxygen delivery to tissues. It increases atherosclerosis risk, which increases the risk of myocardial infarction and death.

Speaking of blood sludge, Midwestern Doctor wrote this excellent article 2 years ago at midwesterndoctor.com/p/why-does-every-vaccine-often-cause which explains that many fluids in the body need to have negative electric charge, called zeta potential, in order to flow well in circulation. When the charge is too low or positive, circulation slows or stops. He says he avoids drinking from aluminum cans or cooking anything in aluminum. Also, some salt is good for zeta potential, but excess causes sludge. And grounding or earthing is also good for zeta potential. The Earth’s surface usually has negative charge, so touching (with your bare skin) the ground or a conductor that’s connected to the ground quickly restores zeta potential in the blood (in ten minutes or so).

COGNITIVE DECLINE
Disruption of the blood-brain barrier is a big new finding. I've been thinking about this lately. I've been reading a lot about causes of cognitive decline, neurodegeneration and there's a surprisingly large amount of information about fat, especially saturated fat (from the articles I've read so far), disrupting the blood-brain barrier and that's going to disrupt the neuronal milieu. The reason you have the blood-brain barrier so the neurons can function with really stable ionic gradients and a real stable external chemistry milieu, so the action potentials fire quickly and everything runs correctly. Disruptions of the blood-brain barrier means fat and other potentially toxic chemicals can get into the brain parenchyma and disrupt neuronal function, so they make you stupider. It can cause a little bit of brain fog and over the long run damage the brain cells and increase risk of dementia. These entire articles written in good journals show the way fat decreases cognitive function and predisposes to Alzheimer's disease.

INSULIN RESISTANCE
Insulin resistance is a much bigger deal than is widely recognized. Not only do you have insulin resistance causing diabetes in your body, but it's also damaging your brain. There are glucose type 4 transformers that are dependent on insulin and are located in your hippocampus, containing your most important memory cells. These transformers are also present in the substantia nigra, very important motor cells for movement. And when you damage hippocampal cells due to excessive fat causing insulin resistance, you run the risk of neuronal apoptosis in your hippocampus and worsening risk of dementia; and in the substantia nigra, worsening risk of Parkinson's disease. So the brain does have a component of glucose-4 transporters that is insulin dependent. And insulin resistance does damage to those areas.

TOXIC ALDEHYDES
OK, next we'll talk about PUFA's. The bottom line is the PUFA's, polyunsaturated fatty acids, {omega-6 and omega-3} put you at risk for lipid peroxidation. {Saturated fats have no double carbon bonds. Instead all of the carbon bonds are saturated with hydrogen. Omega-3 has 3 double carbon bonds at the third, sixth and ninth carbon atom positions. Omega-6 has 2 double carbon bonds at the sixth and ninth carbon position. Omega-9 has 1 double carbon bond, so it's called mono-unsaturated, like olive oil, and the double bond is at the ninth carbon position. The double bonds are weak.} Oxidation can pluck off the methylene bridge and produce toxic aldehydes, like hydroxynonenal. The toxic aldehyde could damage the hippocampus, predisposing to dementia, can damage the hypothalamus, like the arcuate nucleus region, and that can predispose to obesity. It (toxic aldehyde) can damage the pancreas beta cells, increasing the risk of diabetes. And I think that's an increased risk in particular in persons who use a lot of vegetable oil and consume a lot of fried food, even the Omega-3s, which increase the risk of prostate cancer and cause other problems. Their health benefits in the past were exaggerated. Later on it's been shown they're not that healthy. I recommend stay away from them.

CANCER
We talked about blood sludge where you make your tissues ischemic, meaning that you decrease blood oxygen delivery, then you increase the chance of the Warburg effect. That means hypoxia-induced mitochondrial dysfunction, whereby a cell usually dies, but they can transform or differentiate into an anaerobic cell and become cancer. That's the Warburg effect. Whatever tissue culture he put under hypoxia and dropped oxygen delivery by 35% or more, he could induce a lot of cell death, but also cancer. That's why I don't think there's any type of good fats that you should seek out. The small amount of fat you get just from eating plant foods and from the fiber, from the intrinsic fats from the phospholipid fatty acids and whatnot in your plant foods, that's enough. You don't need to seek out any more. And I think all these people looking for good fats are barking up the wrong tree. Worry about lowering your total fat intake and your sodium intake. That's what I would do.

4. FIBER V. OBESOGENS

The Glucose Expert: The Only Proven Way To Lose Weight Fast! Calorie Counting Is A Load of BS! {This is an interview of Robert Lustig.}

OBESOGENS
In your book you talk about environmental obesogens. I've never heard that term before. What does it mean? Obesogens are chemicals in the environment that actually drive weight gain. They caused the differentiation or the growth of fat cells. There are three fat depots in the body. And they're not the same from a metabolic standpoint.

SUBCUTANEOUS FAT
The first fat depot is subcutaneous fat, which resides in the subcutaneous layer, the deepest layer of the skin. It's actually good. It's protective and a place to put excess energy, because it's safe. Eventually you can overload that subcutaneous fat where you will actually make fat vacuoles within the fat cell, that can kill the cell and cause inflammation. The body then secretes proteins called cytokines to restore metabolic function. On average up to about 10 kilos, or 22 lbs, of subcutaneous fat is healthy.

VISCERAL FAT
The second fat depot is belly fat, or visceral fat, the worst type of fat, because of metabolism. It is due to cortisol, which is due to stress. And the reason we know that is because you can take patients with clinical depression, who have no reward from life, no reward from eating, etc. They're gaining visceral fat, because of the cortisol. When you're stressed, you need a readily available and metabolically active source of energy, e.g. in case you're being chased by a lion. You become metabolically ill from only about two kilograms, or 4.4 pounds, of this visceral fat.

LIVER FAT
Finally, the third fat depot is liver fat. You become metabolically ill with only 1/4 kilogram or half a pound. So you can become metabolically ill and be thin. This is skinny fat, thin on the outside, fat on the inside. How does that liver fat get formed? And the answer is sugar and/or alcohol, because the liver is where they go to be processed. That's why so many people now have fatty liver disease. Even children have fatty liver disease even though they don't drink alcohol, because they drink something that is metabolized like alcohol, i.e. fruit juice.

ENVIRONMENTAL OBESOGENS
This apple here is healthy. But if you juice it, you took away the good part, the fiber. And then we've got environmental obesogens, right, which might be on this apple. What and where are they? An obesogen is a chemical that causes weight gain, not because of its calories, but because it causes the differentiation or growth of fat cells and will cause weight gain, unrelated to calories. There are chemicals in our environment that are unescapable, like air pollution and forever chemicals, like PFAS and teflon, non-stick chemicals. Turns out that causes obesity by itself. What they paint on the bottoms of boats to keep barnacles off, gets in the water and the food supply all over the world, so we can't escape them. That causes your fat cells to grow before you're born. BPA, or Bisphenol A, phalanges, i.e. plasticizers, in baby pacifiers, parabens in cosmetics, vinyl flooring, flame retardants in clothing and mattresses. All of these things will drive different receptors in the body and act as endocrine disruptors, which will increase adiposity {fat increase}. They're one of the reasons for the decrease in fertility. So if they're everywhere, what do I do about it? Certainly tap water is going to be a problem, but the fact is some of the bottled water still have obesogens and the obesogen might even be in the bottle. Canned foods have high BPA levels. There are a lot of chemicals in our environment that masquerade as estrogens and BPA is one of them. And estrogen causes fat deposition.

CALORIES
There are also things in our food, that we think are food, such as fructose, that are not. Fructose has calories, true, but fructose has harmful effects on mitochondria that have nothing to do with its calories. In the same way, alcohol has calories, but alcohol has toxic effects that have nothing to do with its calories. So just because something has calories doesn't make it a food. Food is a substance that contributes to either growth or metabolism of an organism. So does ultra-processed food contribute to growth or metabolism? No.

FIBER
Let's talk then about fiber. When they turn an apple into apple juice, they're removing the fibre. Why does that matter? It turns out the fiber is essential for your microbiome. You have to feed your microbiome. We always say when women are pregnant, they're eating for two. Well, we're always eating for 100 trillion in our intestine and what you feed them matters, because if you feed them well, you will have bacterial diversity, and that will actually contribute to metabolic health. It will allow for the barriers in the intestine to work properly, the mucin layer, the tight junctions, the immunologic barrier called the TH 17 cells. Your intestine will present the appropriate barriers so that bad stuff in your intestine won't get into your bloodstream to cause systemic inflammation. So feeding your gut is job one. And what does your gut like to eat? It likes to eat fiber. Now we humans don't have the enzymes to digest fiber, but the bacteria do. When you take the fiber out of the food, you're starving the bacteria. How many grams of fiber are we supposed to eat every day? Our ancestors ate between 50 and 100 grams of fiber a day. In America and the UK, the mean is 12 grams, less than 1/4 the amount our ancestors ate. When you feed fiber to the bacteria, you get metabolic biodiversity, which improves your metabolic health. The bacteria will chew that soluble fiber up into a a compound called short chain fatty acids, like acetate and propionate. Butyrate is particularly helpful as an immune suppressant, keeping your immune system in check. It's one of the reasons that COVID was worse for people who were obese and who had preexisting conditions like metabolic syndrome.